Karel,
Already done it with a Belkin USB bluetooth adapter. Works straight forward and simply once you have trained the signal to the ES2.
However, the problem is....and this occurs with all 3 earsets (Motorola, Nokia and B&O) I have had is that with Skype, there is always a progressive delay forming over time between you and the person you are talking to. So say 10ms becomes 20ms.....and before you know it, there is a 10 second delay.
To overcome this - and I am a big skype user, I have reverted to the Earset 1 Mobile and a aircraft twin mono jack plug. The solution is neat (aparently ES1 can be traditionally soldered to a custon plug) and totally comfortable. Best Skype earpiece I have ever had. Another very underrated B&O product.
So in essence, ES2 is possible but forms a delay. Wire rather than wireless is better.
10%