Hi, if you have Windows Vista, you need the latest version of BeoPlayer/BeoPort (v4.81), the previous ones are not Vista compatible.
I think you also need a BeoSound 6 plugin to make it recognizable by BeoPlayer, the plugin is one the CD ROM that should have been delivered with the BS6.
Finally, if you want to use ITunes and not BeoPlayer, you also need an ITunes plugin which will recognize BS6 when you connect it to your PC and use ITunes.
All plugins can be found on the official B&O website, under "digital media", software downloads.
Good luck!
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