There are lots of other brand video and sound processors out there, that would be wiser selections if you aren't going with the B&O speakers. I consider BeoSystem 3 to be a perfect solution to the needs of any home theatre owner, but that perfection really comes out when you connect B&O screens and speakers to it -- since the processor is calibrated for those.
You can connect other screens and speakers but then you're assembling a "car" with parts from a lot of different models.
Apart from that, there are ways of doing it, of course!